Striking accumulation of PUFA in aged cells

Peat has written many times about the changes that occur in “aged” cells. Those changes are virtually indistinguishable from the ones that occur in “sick” cells and are characterized by reduced mitochondrial number/size and a shift in lipid composition away from saturated and towards unsaturated fats. The crucial mitochondrial lipid enzyme cardiolipin (CL) comprises at … Read more Striking accumulation of PUFA in aged cells

Humans have a ‘salamander-like’ ability to regrow cartilage

The title says it all, but the study authors make the unfortunate/handicapped conclusion that while we may very well be able to regrow cartilage, we cannot regrow limbs. Well, multiple animal studies I posted in the last beg to disagree and point to both high metabolism and progesterone as potent regenerative factors that may be … Read more Humans have a ‘salamander-like’ ability to regrow cartilage

Fertility depends on metabollism (ATP), not age

As many of you know, there are two fundamental dogmas in reproductive medicine. One is that every woman is born with a fixed number of eggs and those cannot be replenished. The second one is that there is a biological fertility clock in every woman that inexorably ticks, and if the female does not have … Read more Fertility depends on metabollism (ATP), not age