Tag: metabolism
High serotonin (5-HT), not low dopamine (DA) per se, as the main driver of Parkinson Disease (PD)
I have several posts on my blog of studies demonstrating that 5-HT antagonists have demonstrated pr-eclinical activity…
PUFA is incompatible with and directly toxic to mammalian mitochondria
This is one of the few studies that presents direct and largely indisputable biochemical evidence for the…
HUMAN STUDY: Niacinamide can help recover from (long) COVID-19
It looks like medicine is starting to look more and more into metabolic therapies for a variety…
Coenzyme Q10 (CoQ10), even at very low doses, improves fertility in both women and men
Once again, the role of metabolism in aspects of health considered completely non-metabolic in nature is being…
Blocking cortisol extends lifespan more than rapamycin, by improving mitochondrial function
Yet another confirmation that cortisol, while being life-saving in acute stress situations, can shorten lifespan if chronically…
Niacinamide increases lifespan and healthspan
An animal study with nicotinamide mononucleotide (NMN). Unfortunately, NMN has been declared as a “novel drug” by…
Vitamin D may be an effective anti-aging intervention
A good summary article on the multitude of mechanisms through which vitamin D acts to target virtually…
Increasing the metabolic rate increases lifespan and improves health
The study below is one of the few to directly challenge the so-called Rate of Living Theory…
US Government: Fluoridated water damages brain and lowers intelligence in humans
Honestly, I did not think that an official government admission of the dangers of fluoride would occur…
Thyroid hormone (T3) promotes curiosity, exploration, novelty-seeking
Curiosity is one of the most common observations in healthy children and is even an established biomarker…