Acidosis (Warburg Effect) drives cancer through increased fat oxidation (Randle Cycle)

The evidence continues to pile on that naming the (in)famous observation made by Otto Warburg in regards to cancer an “effect” is one of the most profound falsehoods the medical profession has ever concocted. Almost a century after the Warburg “Effect” term was coined, the evidence rapidly accumulates that the lactic acidosis is not at … Read more

Elevated maternal estrogen (estradiol) again linked to autism

Just weeks after the first study on the link between elevated estrogens (all types) and autism, a new study again demonstrated a link between elevated maternal estrogen (estradiol in this case) and risk of offspring autism. Estrogen excess during pregnancy may cause autism The studies were performed by different groups of researchers and do not … Read more

Estrogen excess during pregnancy may cause autism

Finally! Some common sense is emerging from the medical profession. For one, it points the finger straight at estrogen as a possible cause of autism. And not just estradiol, which the medical profession considers the only estrogen of note, but all 3 of them (estrone, estradiol, estriol). So, all the talk about estrone/estriol being weak … Read more

SIRT1 is a key promoter of leukemia and other blood cancers

SIRT1 (one of the sirtuin genes) is currently one of the stars in the nutritional/medical blogosphere. As far as back as 2004, SIRT1 was promoted as a key regulator of longevity and activating this gene was marketed as one of the most reliable ways of increasing lifespan. Resveratrol was lauded as one of the most … Read more

PUFA (metabolites) drive heart failure and possibly diabetes

Over the years I have posted a number of studies on the roles of PUFA metabolites such as prostaglandins and leukotrienes in many chronic conditions including cancer, Alzheimer, Parkinson, ALS, MS, CVD, etc. For those that are new to this issue, COX enzymes are responsible for prostaglandin synthesis while LOX enzymes are responsible for leukotriene … Read more

Endotoxin (LPS) may be a major cause of preterm births

As many readers have probably heard, rates of preterm births due to a variety of maternal conditions including (pre)eclampsia has been steadily increasing since the 1980s. The official version is that the cause is unknown despite older studies proving definitively that progesterone deficiency was a major cause and that treatment with progesterone or increasing dietary … Read more

Elevated serotonin increases criminal activity

The study looked at correlations between ambient temperature and criminal activity and found that higher temperatures correlate with reduced SERT density and as such elevated extracellular serotonin. The SERT protein is the one that deactivates serotonin and it is a sodium-dependent protein. Unfortunately, the popular press article that picked up this study included their … Read more

Cheating is driven by cortisol, not testosterone

The topic of macho behavior and its apparent mediator testosterone has been studies every since steroids were discovered. The mainstream dogma states that high testosterone drives cheating behavior (especially of males) as some sort of dominance-asserting behavior of genetically superior organisms. Yet, evidence has been accumulating that cheating, similarly to addiction, is simply a desperate … Read more