{"id":941,"date":"2020-03-22T16:02:57","date_gmt":"2020-03-22T20:02:57","guid":{"rendered":"http:\/\/haidut.me\/?p=941"},"modified":"2020-04-16T14:37:42","modified_gmt":"2020-04-16T18:37:42","slug":"aspirin-a-new-osteoporosis-drug","status":"publish","type":"post","link":"https:\/\/haidut.me\/?p=941","title":{"rendered":"Aspirin &#8211; a new osteoporosis drug"},"content":{"rendered":"<p>A study published almost a decade ago made the bold claim that aspirin may be a novel drug for osteoporosis.<\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21600123\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21600123<\/a><\/p>\n<p>However, the study did not get much traction and was in fact mocked by medical professionals since mainstream medicine considered the known anti-estrogenic effects of aspirin to be incompatible with a bone-protective effect. The study below may finally change this attitude as it provides direct evidence from human trials for the benefits of aspirin.<\/p>\n<p><a href=\"https:\/\/bmjopen.bmj.com\/content\/10\/2\/e026876.full\">https:\/\/bmjopen.bmj.com\/content\/10\/2\/e026876.full<\/a><\/p>\n<p><a href=\"https:\/\/medicaldialogues.in\/orthopaedics\/news\/aspirin-may-increase-bmd-and-reduce-fracture-risk-study-64033\">https:\/\/medicaldialogues.in\/orthopaedics\/news\/aspirin-may-increase-bmd-and-reduce-fracture-risk-study-64033<\/a><\/p>\n<p>&#8220;&#8230;The researchers conducted a systematic review and exploratory meta-analysis of observational studies. This study was published in the\u00a0<a href=\"https:\/\/bmjopen.bmj.com\/content\/10\/2\/e026876.full\" rel=\"nofollow\">British Medical Journal<\/a>. <strong>A total of 12 studies were included in the meta-analysis<\/strong>, Electronic searches of MEDLINE and Embase, and a manual search of bibliographies was undertaken for studies published to 28 March 2018. Studies were included if participants were men or women aged \u226518 years; the exposure of interest was aspirin.Risk of bias was assessed using the Joanna Briggs Institute Critical Appraisal Checklists for observational studies. Following are the findings: 1) Data pooled from six studies that included 511\u2009390 people indicated <strong>aspirin was associated with a 17% lower odds of any fracture<\/strong>. 2) <strong>Aspirin was associated with a higher total hip BMD for women and men<\/strong>. 3) No meta-analyses were undertaken for femoral neck or total body BMD as there were too few studies.&#8221;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A study published almost a decade ago made the bold claim that aspirin may be a novel&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[326,1134,289,12,287,1135,662,53],"class_list":["post-941","post","type-post","status-publish","format-standard","hentry","category-science","tag-aspirin","tag-bmd","tag-bone","tag-inflammation","tag-osteoporosis","tag-prostaglandins","tag-therapeutic","tag-treat","wpcat-2-id"],"_links":{"self":[{"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/posts\/941","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/haidut.me\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=941"}],"version-history":[{"count":2,"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/posts\/941\/revisions"}],"predecessor-version":[{"id":1009,"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/posts\/941\/revisions\/1009"}],"wp:attachment":[{"href":"https:\/\/haidut.me\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=941"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/haidut.me\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=941"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/haidut.me\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=941"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}