The role of vitamin K in bone health is well-established, as is its role as a “coagulation” vitamin (hence its name “K”). However, the role of vitamin K in muscle homeostasis is not well-studied. It is known that vitamin K both stimulates the synthesis of osteocalcin as well as its carboxylation\/activation. It is also well-known that osteocalcin has beneficial effects on muscle mass, likely through the stimulation of androgen synthesis in both male and female gonads. However, a direct link between vitamin K and muscle mass\/strength has not yet been established. The study below is perhaps the first to establish such link, at least in males. Btw, vitamin K has a known synergistic effect with vitamin D for bone mass\/strength, as well as improving insulin sensitivity, and even treating cancer. As such, I would expect the effects of combining vitamin K with vitamin D to be synergistic for muscle mass\/strength as well. And last but not least, handgrip strength is one of the most reliable kinetic biomarkers of overall health, as well as a great predictor of longevity and healthspan. This suggests that vitamin K, especially when combined with vitamin D (already proven lifespan and healthspan booster) may be a great supplement to take for warding off the effects of aging and preventing future chronic disease.<\/p>\n