Not sure if my readers have noticed it, but Big Pharma has drastically increased their bashing of aspirin since the pandemic started. Those attacks began when a few studies published back in 2020 demonstrated that aspirin users had a much lower risk of both contracting and dying from COVID-19, and that aspirin was unique among NSAID in providing such benefits. The bashing of aspirin continues even in the study below, but it is forced to (begrudgingly) admit that low-dose aspirin led to 15% lower risk of developing diabetes in older adults. Now, 15% reduction may not seem like much, but so far there has been no other drug shown to lower risk of developing diabetes. Also, these effects were seen from low-dose aspirin and the pro-metabolic effects of aspirin are known to be dose-dependent (e.g. uncoupling and inhibition of both lipolysis \/ fatty acid oxidation), so higher doses would have likely led to much bigger risk reduction. Of course, the fear-mongering from Big Pharma about aspirin’s dire bleeding risks effectively prevents human trials with higher doses, so unfortunately aspirin probably won’t see much clinical use as prevention\/therapy for diabetes.<\/p>\n
https:\/\/medicalxpress.com\/news\/2023-08-low-dose-aspirin-diabetes-people-aged.html<\/a><\/p>\n “…A total of 16,209 participants were included in the analysis (8,086 randomized to aspirin and 8,123 to placebo). Over a median follow-up of 4.7 years, 995 incident diabetes cases were recorded (aspirin: 459, placebo: 536). Compared with placebo, the aspirin group had a 15% reduction in incident diabetes and a slower rate of increase in FPG (difference in annual FPG change: -0.006 mmol\/L). The authors say, “Aspirin treatment reduced incident diabetes and slowed the increase in fasting plasma glucose over time among initially healthy older adults<\/strong><\/span>. Given the increasing prevalence of type 2 diabetes among older adults, the potential for anti-inflammatory agents like aspirin to prevent type 2\u00a0diabetes<\/a>\u00a0or improve glucose levels needs further study.””<\/p>\n","protected":false},"excerpt":{"rendered":" Not sure if my readers have noticed it, but Big Pharma has drastically increased their bashing of…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[326,285,382,12,850,97,319],"class_list":["post-2307","post","type-post","status-publish","format-standard","hentry","category-science","tag-aspirin","tag-diabetes","tag-fatty-acid-oxidation","tag-inflammation","tag-lipolysis","tag-metabolism","tag-obesity","wpcat-2-id"],"_links":{"self":[{"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/posts\/2307","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/haidut.me\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2307"}],"version-history":[{"count":1,"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/posts\/2307\/revisions"}],"predecessor-version":[{"id":2308,"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/posts\/2307\/revisions\/2308"}],"wp:attachment":[{"href":"https:\/\/haidut.me\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2307"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/haidut.me\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2307"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/haidut.me\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2307"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}