{"id":1917,"date":"2022-07-12T14:20:29","date_gmt":"2022-07-12T18:20:29","guid":{"rendered":"http:\/\/haidut.me\/?p=1917"},"modified":"2022-07-12T14:20:29","modified_gmt":"2022-07-12T18:20:29","slug":"ssri-use-during-pregnancy-increase-risk-of-neonatal-seizures-epilepsy","status":"publish","type":"post","link":"https:\/\/haidut.me\/?p=1917","title":{"rendered":"SSRI use during pregnancy increase risk of neonatal seizures\/epilepsy"},"content":{"rendered":"<p>So much for &#8220;safe and effective during pregnancy&#8221;&#8230;I shudder at the thought of how many women get talked into using SSRI during pregnancy without even having depression. You know, just in case they MIGHT get postpartum depression.<\/p>\n<p><a href=\"https:\/\/n.neurology.org\/content\/neurology\/98\/23\/e2329.full.pdf\">https:\/\/n.neurology.org\/content\/neurology\/98\/23\/e2329.full.pdf<\/a><\/p>\n<blockquote class=\"wp-embedded-content\" data-secret=\"w0TeAeY5rm\"><p><a href=\"https:\/\/www.neurologyadvisor.com\/seizure-disorders\/serotonergic-antidepressant-use-pregnancy-risk-neonatal-seizures\/\">Serotonergic Antidepressant Use in Pregnancy and Risk for Neonatal Seizures<\/a><\/p><\/blockquote>\n<p><iframe loading=\"lazy\" class=\"wp-embedded-content\" sandbox=\"allow-scripts\" security=\"restricted\" style=\"position: absolute; clip: rect(1px, 1px, 1px, 1px);\" title=\"&#8220;Serotonergic Antidepressant Use in Pregnancy and Risk for Neonatal Seizures&#8221; &#8212; Neurology Advisor\" src=\"https:\/\/www.neurologyadvisor.com\/seizure-disorders\/serotonergic-antidepressant-use-pregnancy-risk-neonatal-seizures\/embed\/#?secret=MLGnyWkJj6#?secret=w0TeAeY5rm\" data-secret=\"w0TeAeY5rm\" width=\"500\" height=\"282\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\"><\/iframe><\/p>\n<p>&#8220;&#8230;Researchers at Indiana University in Bloomington used data from the Medical Birth Register in Stockholm, Sweden, to examine the <span style=\"text-decoration: underline;\"><strong>association between reported maternal use of SSRIs or SNRIs and the diagnosis of neonatal seizures or epilepsy<\/strong><\/span> in over 1.2 million children born from 1996 through 2013. Following the evaluation of the\u00a0<a href=\"https:\/\/www.neurologyadvisor.com\/topics\/general-neurology\/new-neuropsychiatric-risks-covid-19-disease-severity\/\">SSRI<\/a> and SNRI use and parental epilepsy, researchers adjusted for a wide range of background factors (eg, age, education, and comorbidities) and pregnancy-specific characteristics (eg, maternal use of tobacco and use of other psychiatric medications). The study found that <span style=\"text-decoration: underline;\"><strong>the children born to women with reported use of SSRIs or SNRIs during pregnancy had 41% greater risk for newborn seizures<\/strong><\/span> (n=1,551,906; risk ratio [RR], 1.41; 95% CI, 1.03-1.94) <span style=\"text-decoration: underline;\"><strong>and 21% increased risk for being diagnosed with epilepsy during follow-up<\/strong><\/span> (n=1,367,087; hazard ratio [HR], 1.21; 95% CI, 1.03-1.43) compared with children who were unexposed to SSRIs or SNRIs. In this study, neonatal seizures and epilepsy were classified using International Classification of Diseases (ICD)-9 and ICD-10. Neonatal seizures were defined by at least 1 diagnosis within the first 30 days of life and epilepsy was defined by at least 1 diagnosis at any time after birth.&#8221;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>So much for &#8220;safe and effective during pregnancy&#8221;&#8230;I shudder at the thought of how many women get&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[192,163,1764,164,47,1614,191],"class_list":["post-1917","post","type-post","status-publish","format-standard","hentry","category-science","tag-5-ht","tag-epilepsy","tag-neonatal","tag-seizures","tag-serotonin","tag-snri","tag-ssri","wpcat-2-id"],"_links":{"self":[{"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/posts\/1917","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/haidut.me\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1917"}],"version-history":[{"count":1,"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/posts\/1917\/revisions"}],"predecessor-version":[{"id":1918,"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/posts\/1917\/revisions\/1918"}],"wp:attachment":[{"href":"https:\/\/haidut.me\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1917"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/haidut.me\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1917"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/haidut.me\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1917"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}