{"id":1897,"date":"2022-06-22T14:59:22","date_gmt":"2022-06-22T18:59:22","guid":{"rendered":"http:\/\/haidut.me\/?p=1897"},"modified":"2022-06-22T14:59:22","modified_gmt":"2022-06-22T18:59:22","slug":"a-real-medical-conspiracy-is-the-reason-for-failure-of-alzheimer-treatments","status":"publish","type":"post","link":"https:\/\/haidut.me\/?p=1897","title":{"rendered":"A real medical &#8220;conspiracy&#8221; is the reason for failure of Alzheimer treatments"},"content":{"rendered":"<p>A meta-review study I posted about years ago stated openly that 99% of all clinical trials for Alzheimer Disease (AD) have failed. It is hard to call this anything but abject, miserable failure pointing to the fact that the hypothesis on the pathology\/origin of AD is dead-wrong. However, it is hard to imagine that billions of dollars and 20+ years have been wasted completely without somebody raising the alarm that maybe medicine is on the wrong track when it comes to AD. Apparently, such alarms have been raised multiple times over the years, but have been brutally suppressed by a true medical cabal attached too strongly politically and financially to the so-called &#8220;beta amyloid hypothesis&#8221;. Namely, the hypothesis that AD is caused by accumulation of misfolded beta-amyloid and tau proteins in the brain. That medical cabal simply refused to allow any new ideas to take hold if those ideas would undermine the generous funding the cabal was enjoying on the back of the taxpayers worldwide. If this level of conspiratorial behavior is not only real, but wit global reach, and lasting for decades, it is hard to imagine that something similar (and likely even more sinister) is happening at the political level in most countries around the world.<\/p>\n<blockquote class=\"wp-embedded-content\" data-secret=\"DmM2imSKd1\"><p><a href=\"https:\/\/www.statnews.com\/2018\/08\/15\/alzheimers-patients-drug-development-outrage\/\">As Alzheimer&#8217;s drug developers give up on today&#8217;s patients, where is the outrage?<\/a><\/p><\/blockquote>\n<p><iframe loading=\"lazy\" class=\"wp-embedded-content\" sandbox=\"allow-scripts\" security=\"restricted\" style=\"position: absolute; clip: rect(1px, 1px, 1px, 1px);\" title=\"&#8220;As Alzheimer&#8217;s drug developers give up on today&#8217;s patients, where is the outrage?&#8221; &#8212; STAT\" src=\"https:\/\/www.statnews.com\/2018\/08\/15\/alzheimers-patients-drug-development-outrage\/embed\/#?secret=lMcgKQg4pO#?secret=DmM2imSKd1\" data-secret=\"DmM2imSKd1\" width=\"500\" height=\"282\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\"><\/iframe><\/p>\n<blockquote class=\"wp-embedded-content\" data-secret=\"GHD1M9Z3e1\"><p><a href=\"https:\/\/www.statnews.com\/2019\/06\/25\/alzheimers-cabal-thwarted-progress-toward-cure\/\">The maddening saga of how an Alzheimer\u2019s \u2018cabal\u2019 thwarted progress toward a cure for decades<\/a><\/p><\/blockquote>\n<p><iframe loading=\"lazy\" class=\"wp-embedded-content\" sandbox=\"allow-scripts\" security=\"restricted\" style=\"position: absolute; clip: rect(1px, 1px, 1px, 1px);\" title=\"&#8220;The maddening saga of how an Alzheimer\u2019s \u2018cabal\u2019 thwarted progress toward a cure for decades&#8221; &#8212; STAT\" src=\"https:\/\/www.statnews.com\/2019\/06\/25\/alzheimers-cabal-thwarted-progress-toward-cure\/embed\/#?secret=MkDrbnVTCB#?secret=GHD1M9Z3e1\" data-secret=\"GHD1M9Z3e1\" width=\"500\" height=\"282\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\"><\/iframe><\/p>\n<p>&nbsp;<\/p>\n<p>&#8220;&#8230;<span style=\"text-decoration: underline;\"><strong>In the 30 years that biomedical researchers have worked determinedly to find a cure for Alzheimer\u2019s disease, their counterparts have developed drugs that helped cut deaths from cardiovascular disease by more than half, and cancer drugs able to eliminate tumors that had been incurable. <span style=\"color: #ff0000; text-decoration: underline;\">But for Alzheimer\u2019s, not only is there <a style=\"color: #ff0000; text-decoration: underline;\" href=\"https:\/\/www.statnews.com\/2018\/08\/15\/alzheimers-patients-drug-development-outrage\/\">no cure<\/a>, there is not even a disease-slowing treatment<\/span><\/strong><\/span>. The brain, Alzheimer\u2019s researchers patiently explain, is hard \u2014 harder than the heart, harder even than cancer. While that may be true, <span style=\"text-decoration: underline;\"><strong>it is increasingly apparent that there is another, more disturbing reason for the tragic lack of progress: The most influential researchers have long believed so dogmatically in one theory of Alzheimer\u2019s that they systematically thwarted alternative approaches. <span style=\"color: #ff0000; text-decoration: underline;\">Several scientists described those who controlled the Alzheimer\u2019s agenda as \u201ca cabal.\u201d<\/span><\/strong><\/span> In more than two dozen interviews, scientists whose ideas fell outside the dogma recounted how, for decades, believers in the dominant hypothesis suppressed research on alternative ideas: They influenced what studies got published in top journals, which scientists got funded, who got tenure, and who got speaking slots at reputation-buffing scientific conferences.&#8221;<\/p>\n<p>&#8220;&#8230;<span style=\"text-decoration: underline;\"><strong>This stifling of competing ideas, say a growing number of scholars, is a big reason why there is no treatment for Alzheimer\u2019s<\/strong><\/span>. (The four approved drugs have no effect on the disease, providing only a temporary memory boost.) The <span style=\"text-decoration: underline;\"><strong>scientists described the frustrating, even career-ending, obstacles that they confronted in pursuing their research<\/strong><\/span>. A top journal told one that it would not publish her paper because others hadn\u2019t. Another got whispered advice to at least pretend that the research for which she was seeking funding was related to the leading idea \u2014 that a protein fragment called beta-amyloid accumulates in the brain, creating neuron-killing clumps that are both the cause of Alzheimer\u2019s and the key to treating it. Others could not get speaking slots at important meetings, a key showcase for research results. Several who tried to start companies to develop Alzheimer\u2019s cures were told again and again by venture capital firms and major biopharma companies that they would back only an amyloid approach. \u201c<span style=\"text-decoration: underline;\"><strong>The amyloid hypothesis has been one of the most tragic stories [in] disease research,\u201d said neurobiologist Rachael Neve of Massachusetts General Hospital<\/strong><\/span>.&#8221;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A meta-review study I posted about years ago stated openly that 99% of all clinical trials for&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[729,1753,1751,1750,925,1752,1754,165],"class_list":["post-1897","post","type-post","status-publish","format-standard","hentry","category-science","tag-alzheimer","tag-beta-amyloid","tag-cabal","tag-conspiracy","tag-failure","tag-hypothesis","tag-tau","tag-treatment","wpcat-2-id"],"_links":{"self":[{"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/posts\/1897","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/haidut.me\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1897"}],"version-history":[{"count":1,"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/posts\/1897\/revisions"}],"predecessor-version":[{"id":1899,"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/posts\/1897\/revisions\/1899"}],"wp:attachment":[{"href":"https:\/\/haidut.me\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1897"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/haidut.me\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1897"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/haidut.me\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1897"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}