Yet another study that should give a pause to all health care providers who push their patients to lose weight at any cost – i.e. “lower is always better”, when it comes to BMI, as the dogma goes. Well, apparently not, according to the study below. The even more astounding fact is that it looks like the ability of malnutrition (involuntary fasting) or even just protein deficiency to cause diabetes was well-known to medicine back in the 1950s-1980s timeframe, yet due to heavy lobbying by Big Pharma that “nutritional” diabetes was removed from the medical books and clinical guidelines. Considering that current guidelines for treating diabetes II call for drastic caloric restriction (a type of malnutrition), this “treatment” approach may explain the rising cases of newly diagnosed diabetes I in adults, which used to be quite rare in the past – i.e. most new cases of diabetes I used to be diagnosed in childhood or late teen years. Another interesting finding of the article was that the malnourished diabetic patients were as insulin-resistant as the diabetes II patients. This suggests that losing weight may not improve the insulin resistance of an overweight, (pre)diabetic patient, which ones again undermines the national health policy to push for weight loss at any cost in at-risk populations.<\/p>\n
https:\/\/diabetesjournals.org\/care\/article\/45\/6\/1428\/146920\/An-Atypical-Form-of-Diabetes-Among-Individuals<\/a><\/p>\n https:\/\/www.the-scientist.com\/news-opinion\/diabetes-linked-to-malnutrition-is-metabolically-unique-study-70138<\/a><\/p>\n “…Between the 1950s and 1980s,\u00a0various<\/a>\u00a0studies<\/a>\u00a0reported the prevalence of diabetes with distinctive features in young people with a history of nutritional deficiency in low- and middle-income countries. The reports motivated the World Health Organization (WHO) to\u00a0create<\/a>\u00a0the category \u201cmalnutrition-related diabetes mellitus.\u201d But in 1999, the same agency\u00a0removed<\/a>\u00a0it as an official category<\/strong><\/span>, based on what it said was a lack of evidence \u201cthat diabetes can be caused by malnutrition or protein deficiency\u00a0per se<\/em><\/strong><\/span>. A clinical study published May 27 in\u00a0Diabetes Care<\/em><\/a>\u00a0now argues that malnutrition-related diabetes mellitus is indeed a distinct type of diabetes, and that studying it as such may improve how it is treated. By studying a small sample of diabetic and healthy males from South India, the authors concluded that diabetic patients with a body mass index (BMI) of 19 kg\/m2<\/sup>\u00a0or below with a history of malnutrition have a defect in insulin secretion<\/strong><\/span>\u2014a feature previously\u00a0suspected<\/a>\u00a0in these diabetic lean populations.\u00a0”<\/p>\n “…By assessing insulin production over the first three hours after a meal, the team found that patients with diabetes and low BMI had significantly lower insulin secretion than those with type 2 diabetes, but higher than those with type 1. On the other hand, insulin resistance was on the whole significantly lower in the lean diabetes patients than in type 2 diabetes. A few of these lean participants were as insulin resistant as those in type 2 patients, though, \u201cand maybe, if we studied hundreds of [them], we would start to see subgroups,\u201d says Hawkins. But for these lean diabetes subjects, the major problem was insulin secretion, not insulin resistance, she notes. The research team hypothesizes that this secretion failure may result from decreased beta cell mass, a feature that has been associated with maternal low-protein diets in\u00a0mice<\/a>. Weanling rats fed with a low protein diet also\u00a0show<\/a>\u00a0a marked defect in insulin secretion. While low protein intake may be the main culprit in impaired beta cell function in malnourished diabetic populations<\/strong><\/span>, Hawkins explains that other nutritional deficiencies could also play a role<\/strong><\/span>. For example, \u201ca lot of micronutrients like zinc can be extremely important in improving insulin secretion and improving beta cell function<\/strong><\/span>,\u201d she says.”<\/p>\n","protected":false},"excerpt":{"rendered":" Yet another study that should give a pause to all health care providers who push their patients…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[1739,315,285,314,983,1738,1717],"class_list":["post-1888","post","type-post","status-publish","format-standard","hentry","category-science","tag-bmi","tag-caloric-restriction","tag-diabetes","tag-fasting","tag-malnutrition","tag-protein-deficiency","tag-zinc","wpcat-2-id"],"_links":{"self":[{"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/posts\/1888","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/haidut.me\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1888"}],"version-history":[{"count":1,"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/posts\/1888\/revisions"}],"predecessor-version":[{"id":1889,"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/posts\/1888\/revisions\/1889"}],"wp:attachment":[{"href":"https:\/\/haidut.me\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1888"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/haidut.me\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1888"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/haidut.me\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1888"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}