{"id":1491,"date":"2021-04-27T14:48:14","date_gmt":"2021-04-27T18:48:14","guid":{"rendered":"http:\/\/haidut.me\/?p=1491"},"modified":"2021-04-27T14:49:42","modified_gmt":"2021-04-27T18:49:42","slug":"endocrine-disruptor-in-cosmetic-products-may-cause-postpartum-depression-ppd","status":"publish","type":"post","link":"https:\/\/haidut.me\/?p=1491","title":{"rendered":"Endocrine disruptors in cosmetics may cause postpartum depression, premature births"},"content":{"rendered":"

Hardly a surprising finding, but it will probably come as a shock to most modern women who are the biggest consumers of such products (e.g. nail polish, perfumes, shampoo, etc). One of the reasons for this “controversy” is that doctors continue to insist that using such products during pregnancy is perfectly safe, for both mom-to-be and baby. Importantly, the mechanism through which the phthalates<\/a>, the endocrine disruptor in question, cause PDD is by lowering levels of progesterone and as such its metabolite allopregnanolone (which was recently approved by FDA as treatment for PPD<\/a>). Since progesterone is the main pregnancy-preserving (tocolytic) hormone, the study findings also suggest that exposure to these chemicals may trigger premature birth and\/or abortion. Considering that phthalates are estrogenic and act as thyroid antagonists similarly to the (in)famous plastic ingredients BPA\/BPS, the link between phthalates and PPD and their effects on hormonal balance reported in this study are hardly surprising.<\/p>\n

https:\/\/academic.oup.com\/jcem\/advance-article-abstract\/doi\/10.1210\/clinem\/dgab199\/6189805?redirectedFrom=fulltext<\/a><\/p>\n

“…Di-n-octyl phthalate (DnOP) and diisononyl phthalate (DiNP) metabolites were associated with reduced progesterone concentrations<\/span><\/strong><\/span>. Log-unit increases in \u2211DnOP and \u2211DiNP predicted 8.1% (95% Confidence Interval (CI): -15.2%, -0.4%) and 7.7% (95% CI: -13.3%, -1.7%) lower progesterone<\/span>, respectively. \u2211DnOP was associated with increased odds of PPD (odds ratio=1.48 (95% CI: 1.04, 2.11)). Conclusions: Endocrine disrupting chemicals may influence hormonal shifts during pregnancy as well as contribute to PPD<\/span><\/strong><\/span>.”<\/p>\n

https:\/\/www.romper.com\/life\/study-exposure-chemicals-plastics-beauty-products-postpartum-depression<\/a><\/p>\n

“…A new study published in the\u00a0Endocrine Society’s Journal of Clinical Endocrinology & Metabolism<\/em>\u00a0suggests there may be a\u00a0link between postpartum depression and exposure to chemicals<\/a>\u00a0found in plastics and beauty products such as nail polish, shampoo, and perfume. Researchers found\u00a0endocrine-disrupting chemicals called phthalates may influence hormonal shifts<\/a> and contribute to postpartum depression. \u201cPhthalates are a class of chemicals used in plastics and personal care products that have been shown to affect and interfere with endogenous hormones<\/strong><\/span>,\u201d Melanie Jacobson, the study\u2019s lead author and an epidemiologist and research scientist at the\u00a0NYU Langone Medical Center<\/a> in New York, tells Romper. \u201cTheir use is so widespread that nearly all U.S. adults, including pregnant women, have detectable levels in their systems<\/strong><\/span>.\u201d According to the U.S. Food and Drug Administration (FDA),\u00a0phthalates can prolong a fragrance’s shelf life<\/a> and increase the flexibility of plastic. They\u2019re found in a wide array of products, including toys, vinyl flooring, detergents, food packagings, and personal care products like nail polish, hair sprays, aftershave lotions, soaps, shampoos, and perfumes<\/strong><\/span>. In nail polish, for example, phthalates known as dibutylphthalate serve as a plasticizer, essentially working to reduce cracking within the polish. In hair spray, phthalates known as dimethylphthalate help create the flexible hold users love. In perfumes, phthalates known as diethylphthalate helps preserve the fragrance.”<\/p>\n","protected":false},"excerpt":{"rendered":"

Hardly a surprising finding, but it will probably come as a shock to most modern women who…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[1515,17,158,1512,1513,1514,709,153],"class_list":["post-1491","post","type-post","status-publish","format-standard","hentry","category-science","tag-abortion","tag-allopregnanolone","tag-endocrine-disruptor","tag-phthalates","tag-post-partum-depression","tag-ppd","tag-preterm","tag-progesterone","wpcat-2-id"],"_links":{"self":[{"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/posts\/1491","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/haidut.me\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1491"}],"version-history":[{"count":3,"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/posts\/1491\/revisions"}],"predecessor-version":[{"id":1494,"href":"https:\/\/haidut.me\/index.php?rest_route=\/wp\/v2\/posts\/1491\/revisions\/1494"}],"wp:attachment":[{"href":"https:\/\/haidut.me\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1491"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/haidut.me\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1491"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/haidut.me\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1491"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}